methuselah proposition

compiled bob ray | DECEMBER 28, 2022

EDITED BY: ARIEL

Aviv Clinic is a hyperbaric oxygen pressure-based treatment that primarily focuses on keeping the brain young or younger.

There are 3 locations: The Villages, Florida, Dubai UAE, and Tel Aviv.

The treatment lasts 8 to 12 weeks, 5 days per week. 2-3 hours per day. Hyperbaric Oxygen Treatment costs about $60,000.

While it may make you poorer, it should make you younger. They even include golf lessons if you want to lower your handicap.

NEWS RELEASE 19-NOV-2020

The first clinical trial reverses two biological processes associated with aging in human cells.

AMERICAN FRIENDS OF TEL AVIV UNIVERSITY

A new study from Tel Aviv University (TAU) and the Shamir Medical Center in Israel indicates that hyperbaric oxygen treatments (HBOT) in healthy aging adults can stop the aging of blood cells and reverse the aging process. In the biological sense, the adults’ blood cells actually grow younger as the progress of treatment.

The researchers found that a unique protocol of treatments with high-pressure oxygen in a pressure chamber can reverse two major processes associated with aging and its illnesses: the shortening of telomeres (protective regions located at both ends of every chromosome) and the accumulation of old and malfunctioning cells in the body. Focusing on immune cells containing DNA obtained from the participants’ blood, the study discovered a lengthening of up to 38% of the telomeres, as well as a decrease of up to 37% in the presence of senescent cells.

The study was led by Professor Shai Efrati of the Sackler School of Medicine and the Sagol School of Neuroscience at TAU and Founder and Director of the Sagol Center of Hyperbaric Medicine at the Shamir Medical Center; and Dr. Amir Hadanny, Chief Medical Research Officer of the Sagol Center for Hyperbaric Medicine and Research at the Shamir Medical Center. The clinical trial was conducted as part of a comprehensive Israeli research program that targets aging as a reversible condition.

The paper was published in Aging on November 18, 2020.

“For many years our team has been engaged in hyperbaric research and therapy – treatments based on protocols of exposure to high-pressure oxygen at various concentrations inside a pressure chamber,”

Professor Efrati explains. “Our achievements over the years included the improvement of brain functions damaged by age, stroke, or brain injury."

“In the current study, we wished to examine the impact of HBOT on healthy and independent aging adults, and to discover whether such treatments can slow down, stop or even reverse the normal aging process at the cellular level.”

The researchers exposed 35 healthy individuals aged 64 or over to a series of 60 hyperbaric sessions over a period of 90 days.

Each participant provided blood samples before, during, and at the end of the treatments as well as some time after the series of treatments concluded.

The researchers then analyzed various immune cells in the blood and compared the results.

The findings indicated that the treatments actually reversed the aging process in two of its major aspects: The telomeres at the ends of the chromosomes grew longer instead of shorter, at a rate of 20%-38% for the different cell types; and the percentage of senescent cells in the overall cell population was reduced significantly – by 11%-37% depending on cell type.

“Today telomere shortening is considered the ‘Holy Grail’ of the biology of aging,” Professor Efrati says. “Researchers around the world are trying to develop pharmacological and environmental interventions that enable telomere elongation. Our HBOT protocol was able to achieve this, proving that the aging process can in fact be reversed at the basic cellular-molecular level.”

“Until now, interventions such as lifestyle modifications and intense exercise were shown to have some inhibiting effect on telomere shortening,” Dr. Hadanny adds. “But in our study, only three months of HBOT were able to elongate telomeres at rates far beyond any currently available interventions or lifestyle modifications.

With this pioneering study, we have opened a door for further research on the cellular impact of HBOT and its potential for reversing the aging process.”

People often compare the Villages to Disney World, given the themed town centers. But Glenn Colarossi, the head of Aviv’s business development and my host, likens it to a college campus for the retired. “They like to have fun,” he observes.

The Villages is reimagining our notion of the golden years, and Aviv is greasing the wheels—and joints—of this revolution. Its goal, Colarossi tells me, is to increase a person’s “health span,” not just their life span content.

MEN'S HEALTH

Pioneered by Israeli physician Shai Efrati, M.D., the clinic studies each client down to their DNA and constructs a personalized plan for staying physically and mentally healthy.

The centerpiece is hyperbaric oxygen therapy (HBOT), in which patients breathe pure oxygen at varying pressures in a hyperbaric chamber, potentially inducing cell growth and expanding blood vessels in the brain.

The original research center in Israel opened 15 years ago, and the Florida site opened in March 2020. If I were entering the 12-week program, I’d meet with a physical therapist, a physiologist, a doctor, and a dietitian; engage with millions of dollars worth of machinery; and submit DNA, which would result in a 200-page book of codes and genetic indicators that each of the experts would parse.

There would be 60 sessions in the hyperbaric chamber as well as before-and-after MRI and SPECT brain scans. The program cost: $60,000.

Is this just another get-young-quick fad for the rich and yet another reminder of our healthcare system’s inequalities? Or do HBOT and a customized evaluation of your physiology offer some chance to counteract declining brain and body function and help in the fight we all eventually fight—the one against aging?

Hyperbaric Oxygen Chamber

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copyright 2022 bob ray | edited by ariel